People with bipolar disorder are particularly light sensitive at night and their melatonin production gets easily suppressed by blue light at the wrong hours of the day. Many researchers now believe that bipolar disorder is related to problems with maintaining a stable circadian rhythm.

Chrono Chrome's virtual darkness eyewear helps to stabilize the circadian rhythm and promotes calmness before going to bed.

Research on the use of virtual darkness for patients with bipolar disorder, in the euthymic phase, showed improved sleep for the majority of the patients (Phelps 2007). 

The first case report on patients, in the manic episode, using virtual darkness eyewear demonstrated a rapid decline in manic symptoms. The patients’ sleep patterns also improved from very irregular to very regular (Henriksen et al. 2014). A recent randomized placebo-controlled trial showed that virtual darkness eyewear was also effective, feasible and safe as add-on treatment for mania (Henriksen et al. 2016).